流行病学调查显示,糖尿病患者中ED的发病率为19.5%~75.2%~([1,2])。随着糖尿病发病率的不断升高,糖尿病勃起功能障碍(DMED)的发病率也日渐增高,预计我国到2025年DMED患者会达到4000万~([3])。对疾病的发病机制进行研究可以指导临床诊疗,而制备合适的动物模型是进行高质量实验研究的前提。本 Epidemiological survey showed that the incidence of ED in diabetic patients was 19.5% ~ 75.2% ~ ([1,2]). With the rising incidence of diabetes, the incidence of diabetic erectile dysfunction (DMED) is also increasing. It is estimated that 40 million DMED patients in our country will reach 40 million in 2025. The study of the pathogenesis of the disease can guide the clinical diagnosis and treatment, and the preparation of a suitable animal model is the premise of high-quality experimental study. this