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十九世纪末以来,不断证明肿瘤与细胞免疫关系密切,其中以E-玫瑰花形成方法测量循环血中T-淋巴细胞百分比的变化,是检验病人细胞免疫水平方法之一。本文报告在25例喉及喉咽鳞癌病人及10例健康对照者,测量其循环血中淋巴细胞的E-玫瑰花结花率。其中喉癌11例,均为男性(声门上癌4例,声门癌6例,声门下癌1例);喉咽癌14例,男性9例,女性5例(环后癌7例,梨状窝癌7例)。病人按TNM分类,Ⅰ期2例,Ⅱ期5例,Ⅲ期5例,Ⅳ期13例。以Wybran(1973)方法测量循环血中淋巴细胞与绵羊红细胞形成玫瑰花的T-淋巴细胞数,分别计算活性E-玫瑰花结花率和总E-玫瑰花的结花率。结果发现,癌瘤组病人,总结花率为30～60%,平均为44.18±7.922%;对照组为58～
Since the late nineteenth century, it has been proved that tumors are closely related to cellular immunity. Among them, the method of measuring the percentage of T-lymphocytes in circulating blood by the method of formation of E-rosette is one of the methods to test the level of cellular immunity in patients. This article reports 25 cases of laryngeal and hypopharyngeal squamous cell carcinoma patients and 10 healthy controls were measured circulating blood lymphocytes E-rose flower rate. Including laryngeal cancer in 11 cases, were male (supraglottic carcinoma in 4 cases, glottic carcinoma in 6 cases, subglottic cancer in 1 case); hypopharyngeal carcinoma in 14 cases, 9 males and 5 females (7 cases of posterior ring cancer, 7 cases of pear-shaped nest cancer). According to TNM classification, patients in stage Ⅰ were 2 cases, stage Ⅱ in 5 cases, stage Ⅲ in 5 cases and stage Ⅳ in 13 cases. The numbers of T-lymphocytes in the circulating blood lymphocytes and the sheep erythrocytes forming roses were measured by the method of Wybran (1973), and the rate of active E-rose flowers and the total rate of E-rose flowers were calculated. The results showed that cancer patients, the rate of summary of 30 to 60%, with an average of 44.18 ± 7.922%; control group of 58 ~