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目的评价胃食管反流病调查评分量表(Gerd Q)对胃食管反流病(GERD)患者初步诊断中的应用价值。方法采用随机抽样法选取收集自2015年6月~2016年6月,在新疆维吾尔自治区人民医院微创、疝与腹壁外科疑似GERD患者350例,应用Gerd Q评分量进行评分,并进行专科处理,进一步完善内镜、食管24 h PH检测和(或)质子泵抑制剂(proton pump inhibitor,PPI)诊断实验等进一步确诊,并与Gerd Q值进行比较,最后计算出诊断GERD的临界值进而分析Gerd Q量表在诊断GERD中的价值。结果 GERD患者中Gerd Q积分主要集中于7~14分,非GERD组主要集中于7分以下,差异有统计学意义(P<0.05);Gerd Q诊断临界值升高后,其灵敏度逐渐降低,特异度逐渐升高,Gerd Q评分量表以8分为临界值时,ROC曲线下面积为0.802,其敏感性和特异性分别为77.50%和87.31%,Youden指数0.648,对GERD患者诊断的阳性符合率为77.72%,阴性符合率为87.8%。结论 Gerd Q量表是GERD的良好筛查工具之一,敏感性和特异性较高,可用于GERD的初步诊断。
Objective To evaluate the value of Gerd Q in the preliminary diagnosis of gastroesophageal reflux disease (GERD). Methods A total of 350 patients with suspected GERD underwent minimally invasive, hernia and abdominal wall surgery in People’s Hospital of Xinjiang Uygur Autonomous Region from June 2015 to June 2016 were selected by random sampling method. The scores of Gerd Q were graded and treated with specialties. Further refinement of endoscopic, esophageal 24 h PH detection and / or proton pump inhibitor (PPI) diagnostic tests were further confirmed and compared with Gerd Q values, and finally the critical value of diagnosis of GERD was calculated and Gerd Q scale in the diagnosis of GERD value. Results Gerd Q scores of GERD patients were mainly concentrated in 7-14 points, non-GERD patients were mainly concentrated in 7 points or less, the difference was statistically significant (P <0.05). The sensitivity of Gerd-Q diagnosis decreased gradually, The specificity of the Gerd Q scale was 8 points. The area under the ROC curve was 0.802, with a sensitivity and specificity of 77.50% and 87.31%, respectively. The Youden index was 0.648. The positive diagnosis of GERD The coincidence rate was 77.72%, the negative coincidence rate was 87.8%. Conclusion The Gerd Q scale is a good screening tool for GERD. It has high sensitivity and specificity and can be used for the preliminary diagnosis of GERD.