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目的：：比较乌拉地尔与尼卡地平对老年高血压急症患者儿茶酚胺与心率的影响。方法：将我院2011年9月~2013年9月收治的120例老年急症高血压患者随机分作A组与B组，每组各60例， A组给予乌拉地尔治疗， B组给予尼卡地平治疗。记录与比较两组患者治疗前、治疗1h时以及出院前的心率与血压值，同时检测两组患者肾上腺素与去甲肾上腺素的浓度。结果： A组与B组降压效果无统计学差异，两组治疗后各时间点的HR相比，无统计学差异( P>0．05)， A组治疗后的心率较治疗前明显减小(P0．05)，同出院前相比，具统计学差异(P0．05)。结论：乌拉地尔与尼卡地平治疗老年高血压急症均可有效、快速、平稳地降低血压，短期内不会引起儿茶酚胺上升。“,”OBJECTIVE: To discuss the effect of Urapidil and Nicardipine on catecholamies and heart rate in the senile patients with hypertension. METHODS: 120 patients in our hospital from September 2011 to September 2013 were divided randomly into group A (n=60) and group B (n=60). Group A accepted urapidil and group B received nicardipine treatment. Heart rate and the value of blood pressure were recorded and compaired before treatment, at 1 hour of the treatment and before discharge in two groups. The concentration of epinephrine and norepinephrine was detected. RESULTS: There was no statistically differences in antihypertensive effect in two groups. There was no significant difference at different time points compared to HR after treatment in two group (P>0. 05). In group A HR after treatment decreased significantly than that before treatment (P<0. 05). In group B there was no statis-cally difference in HR at 1 hour of the treatment compared with that before treatment, but there was statiscally difference compared with that before discharge (P<0. 05). Serum E and NE levels were not changed, and there was no statistically difference (P<0. 05 ) . CONCLUSIONS: Urapidil and nicardipine can decrease the blood pressure effectively in the elderly patients with hypertensive e-mergencies and may not increase catecholamine level during shor time.