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渐增浓度的哌啶（０．０１～１．０μｍｏｌ／Ｌ１）抑制电场利激引起的豚鼠离体支气管内的胆碱能神经和感觉神经Ｃ纤维的兴奋作用，该作用可被纳洛酮阻断．哌啶不抑制卡巴可引起的支气管平滑肌收缩，也不抑制电场刺激引起的离体气管的松弛作用．说明哌啶通过μ阿片受体介导，具有抑制豚鼠气道内的兴奋性神经末梢的功能。
Increasing concentrations of piperidinium (0.01-1.0 μmol / L) inhibited the excitation of cholinergic nerve and sensory nerve C fibers in isolated guinea pig bronchial tubes induced by electric field stimulation. This effect could be inhibited by naloxone Blocked. Piperidine did not inhibit the cardiomyocyte-induced bronchial smooth muscle contraction, and did not inhibit the relaxation of the isolated trachea caused by electrical stimulation. It is shown that piperidin is mediated by mu opioid receptor and has the function of inhibiting excitatory nerve endings in the airway of guinea pig.