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目的观察盐酸贝那普利对老年高血压心脏病患者的降压疗效及其对左室肥厚的逆转和舒张功能的改善作用。方法选择老年高血压伴左室肥厚患者66例,给予口服盐酸贝那普利10 mg,1次/d,总疗程6个月。以彩色多普勒超声心动图观察治疗前、后心脏结构和舒张功能的改变情况。结果老年高血压心脏病患者治疗后收缩压、舒张压均有所下降。室间隔舒张末期厚度(IVSD)、左室后壁舒张末期厚度(LVPWD)较治疗前明显减轻。结论盐酸贝那普利能有效逆转高血压患者左心室肥厚,明显改善左心室舒张功能。
Objective To observe the antihypertensive efficacy of benazepril hydrochloride in elderly hypertensive heart patients and its effect on the reversal and diastolic function of left ventricular hypertrophy. Methods Sixty-six elderly hypertensive patients with left ventricular hypertrophy were enrolled in this study. The patients were given oral benazepril 10 mg once daily for a total of 6 months. Color Doppler echocardiography before and after treatment to observe changes in cardiac structure and diastolic function. Results After treatment, systolic blood pressure and diastolic blood pressure of elderly hypertensive heart patients decreased. Interventricular septum end-diastolic thickness (IVSD) and left ventricular posterior wall end-diastolic thickness (LVPWD) were significantly lower than those before treatment. Conclusion benazepril hydrochloride can effectively reverse left ventricular hypertrophy in hypertensive patients and significantly improve left ventricular diastolic function.