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目的 探讨神经导航和电生理监测在中央沟附近病变切除术中的应用。方法 本院收治的14例中央沟附近病变患者,在神经导航和电生理监测下行显微手术切除病变,观察其临床疗效。结果 本组中病变全切除9例,大部分切除5例。术后出现对侧肢体肌力减退2例,偏瘫1例,术前肢体肌力减退加重2例,3例肢体运动障碍者术后1个月左右好转。结论 联合应用神经导航和电生理监测技术在中央沟附近病变切除术中具有较大的临床实用价值。“,”Objective]To explore the application of neuronavigation and electrophysiological monitoring in the resection of lesions near the central sulcus .[Methods]A total of 14 patients with lesions near the central sulcus in our hospital underwent microsurgical procedures assisted with neuronavigation and electrophysiological monito‐ring .Clinical efficacy was observed .[Results]In the group ,9 patients underwent total resection and 5 patients un‐derwent partial resection .After operation ,contralateral limb muscle strength impairment occurred in 2 patients af‐ter operation ,and hemiplegia occurred in 1 patient ,and limb muscle strength impairment was aggravated in 2 pa‐tients .The 3 patients with limb movement disorder got better about one month after operation .[Conclusion]The combination of intraoperative neuronavigation and electrophysiological monitoring is of great clinical practical value in the resection of lesions near the central sulcus .