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纯化的鸡胚细胞狂犬病疫苗（PCECV）是目前印度最为常用的组织培养疫苗,本文报告两例应用PCECV后出现的皮肤不良反应。 第1例,1名6岁男孩在背部被狗严重咬伤后被送入医院,每天接种3ml Semple疫苗。第3次接种后因出现荨麻疹型皮疹而停止接种。改以5剂PCECV肌肉注射。第2次接种后再次出现类似皮疹,在应用抗组胺药的情况下完成全程接种。患儿及其父母是严格的素食者,因此他对鸡蛋的敏感性不能确定。第2例为18月龄幼儿,因饮用疑患狂犬病牛的奶而肌肉接种PCECV。每次接种后1或2天,出现荨麻疹型皮疹。反应轻微,故完成全程接种。已知患儿对鸡蛋不过敏。
The purified chicken embryo cell rabies vaccine (PCECV) is currently the most commonly used tissue culture vaccine in India. This article reports two cases of skin adverse reactions that occur after the application of PCECV. In the first case, a 6-year-old boy was admitted to the hospital after a severe back bite was bitten by a dog and was given a daily 3 ml Semple vaccine. Vaccination was stopped after the third vaccination due to urticaria. Change to 5 PCECV intramuscular injection. A second rash occurred after the second inoculation, completing the full vaccination with antihistamines. Children and their parents are strictly vegetarian, so his sensitivity to eggs can not be determined. The second case was a 18-month-old child who was intramuscularly inoculated with PCECV by drinking the milk of suspected rabies cow. Urticaria-type rash occurs 1 or 2 days after each vaccination. Slight reaction, so complete the whole vaccination. Children are not known to be allergic to eggs.