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与其他荧光纳米粒子相比,荧光碳纳米颗粒不仅具有良好的生物相容性和易于表面功能化等优点,还具有发光稳定并可实现上转换荧光发射的特性,所以在生物医药领域有重要的应用价值。本文结合近年来的最新研究成果,综述了金刚石、石墨和非晶等不同结构的荧光碳纳米颗粒的制备方法及其局限性;分析了不同结构碳纳米颗粒的荧光发射特性和在生物技术中应用的优缺点;阐述了荧光碳纳米颗粒在今后研究中需要解决的问题和发展方向。
Compared with other fluorescent nanoparticles, fluorescent carbon nanoparticles not only have the advantages of good biocompatibility and ease of surface functionalization, but also have the characteristics of stable luminescence and up-conversion fluorescence emission. Therefore, it is important in the field of biomedicine Value. Based on the latest research results in recent years, the preparation methods and limitations of fluorescent carbon nanoparticles with different structures such as diamond, graphite and amorphous are summarized. The fluorescence emission characteristics of different structured carbon nanoparticles are analyzed and applied in biotechnology The advantages and disadvantages of the fluorescent carbon nanoparticles; the problems and the development direction of the fluorescent carbon nanoparticles in the future research are expounded.