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目的通过对威海市2011~2013年未分型肝炎与甲、丙、戊肝的流行特征进行比较,及对未分型肝炎进行戊肝再检测,以对未分型肝炎潜在分型进行探讨。方法对2011~2013年通过传染病报告系统报告的甲、丙、戊肝和未分型肝炎的发病时间、人群和空间分布进行分析,并对部分未分型肝炎再次进行实验室检查,从而估计未分型肝炎的分型。结果2011~2013年,甲、丙、戊和未分型肝炎年均报告发病率分别为1.75/10万、6.14/10万、7.05/10万、6.24/10万(P<0.05、P>0.05)。丙肝、戊肝和未分型肝炎的发病年龄均以40~69岁的中老年年龄组为主,该年龄组病例数分别占全部病例数的分别占全部病例数的62.27%、73.86%、65.71%。发病时间以3~4月为发病高峰。甲肝、丙肝的发病率以环翠区最高,分别达到8.89/10万和34.52/10万;戊肝和未分型肝炎的发病地理分布均以乳山市最高,达到48.69/10万和41.98/10万以上。对未分型肝炎的再次实验室检测证实,有23例(51.11%)的未分型肝炎证实为戊肝病例。结论未分型肝炎与戊肝流行特征相近,应对未分型肝炎进一步进行戊肝相关检测,提高未分型肝炎的分型率。
Objective To compare the epidemiological characteristics of non-typed hepatitis and A, C and E in Weihai from 2011 to 2013, and to reheal the hepatitis E in non-typed hepatitis to explore the potential classification of non-typed hepatitis. Methods The incidence, population, and spatial distribution of hepatitis A, C, E and hepatitis H reported through the Communicable Disease Reporting System from 2011 to 2013 were analyzed, and some un-segregated hepatitis was retested in laboratory to estimate Classification of undifferentiated hepatitis. Results The annual average reported incidence rates of hepatitis A, C, E and non-segmented hepatitis were 1.75 / 100,000, 6.14 / 100,000, 7.05 / 100,000 and 6.24 / 100,000 respectively from 2011 to 2013 (P> 0.05, P> 0.05 ). The age of onset of hepatitis C, hepatitis E and undifferentiated hepatitis were mainly in the middle-aged and 40- to 69-year-old age groups, accounting for 62.27%, 73.86% and 65.71 of the total number of cases in this age group respectively %. The onset time to 3 to 4 months as the peak incidence. The incidence of hepatitis A and hepatitis C was the highest in Huancui district, reaching 8.89 / 100000 and 34.52 / 100000, respectively. The incidence of hepatitis E and non-segregating hepatitis were highest in Rushan, reaching 48.69 / 100000 and 41.98 / 10 Million or more. A second lab test on undifferentiated hepatitis confirmed 23 cases (51.11%) of undifferentiated hepatitis confirmed as hepatitis E cases. Conclusion The characteristics of unheated hepatitis and epidemiological characteristics of hepatitis E are similar, and should be further detected for hepatitis E associated with non-classified hepatitis, and to improve the typing rate of unfractionated hepatitis.