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我科1931～1934年经心电图检查确诊新生儿Q-T 间期延长121例。男96例,女25例。日龄<24小时11例(33.9)%;～3天31例(25.6%);～7天13例(10.7%),～28天36例(29.7%)。早产儿61例(51.3%)过期产2例(1.7%)。体重<1500克17例;～2499克56例;～3999克45例;>4000克3例。患儿有产时窒息49例,异常胎位24例。临床表现体温不升92例(76%);硬肿68例(56.2%);黄疸32例(26.14%);心音低钝58例(47.9%),心脏杂音5例(41.%),心脏扩大1例(3.3%),另外还有气急、青紫、苍白、拒乳、反应差、肌力低下等。原发疾病中败血症42例,肺炎44例,颅内出血19例,肺透明膜病8例。心电图检查Q-T 间期延长同时伴心动过缓51例,心动过速5例;Ⅰ°房室传导阻滞26例,低电压25例,T 波及ST 段改变35例,存活者随访Q-T 间期均恢复正常。引起新生儿Q-T 间期延长的病因有:心肌损伤(中毒、缺氧),中枢神经系统疾患,代谢紊乱(低血钾、低血钙、低血糖),低体温及硬肿症。
Our department from 1931 to 1934 confirmed by electrocardiogram Q-T neonatal extension of 121 cases. 96 males and 25 females. There were 11 cases (33.9%) at day 24, 31 cases (25.6%) at 3 days, 13 cases (10.7%) at 7 days and 36 cases (29.7%) at 28 days. Premature children 61 cases (51.3%) 2 patients (1.7%) were overdue. Body weight <1500 g in 17 cases; ~ 2499 g in 56 cases; ~ 3999 g in 45 cases;> 4000 g in 3 cases. Children with asphyxia in 49 cases, 24 cases of abnormal fetal position. The clinical manifestations were as follows: 92 cases (76%) did not rise in temperature, 68 cases (56.2%) had sclerosis, 32 cases (26.14%) had jaundice, 58 cases (47.9% Expand in 1 case (3.3%), in addition there are shortness of breath, bruising, pale, refused to milk, poor response, low strength and so on. 42 cases of sepsis in primary disease, 44 cases of pneumonia, intracranial hemorrhage in 19 cases, 8 cases of hyaline membrane disease. ECG QT prolonging at the same time with bradycardia in 51 cases, tachycardia in 5 cases; Ⅰ ° atrioventricular block in 26 cases, 25 cases of low voltage, T wave and ST segment changes in 35 cases, the survival of QT were Back to normal. Cause of neonatal Q-T prolongation of the etiology: myocardial injury (poisoning, hypoxia), central nervous system disorders, metabolic disorders (hypokalemia, hypocalcemia, hypoglycemia), hypothermia and scleredema.