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目的探讨维吾尔族子痫前期患者血清微量元素锌、铜、铁、锰的变化,指导子痫前期的预防及临床治疗。方法用日立7600型自动生化分析仪及罗氏自动生化分析仪测定子痫前期轻度孕妇血清维吾尔族、汉族各30例,新生儿脐血清维吾尔族、汉族各30例。子痫前期重度患者血维吾尔族、汉族各36例,新生儿脐血清维吾尔族、汉族各36例的钙、镁、锌、铁、铜含量并进行对照研究。结果子痫前期轻度汉族母血清铁、钙、镁含量高于维吾尔族,差别有统计学意义(P<0.05),汉族铜低于维吾尔族,锌高于维吾尔族,但差异无统计学意义(P>0.05);子痫前期重度组汉族母血清钙、镁、锌含量高于维吾尔族,差别有统计学意义(P<0.05),汉族铁高于维吾尔族,铜低于维吾尔族,但差异无统计学意义(P>0.05)。结论维吾尔族与汉族患者微量元素锌、铜、钙、镁的含量有差异且与子痫前期的发生及病情发展有一定的相关性。可能由于生活习惯以及信仰习俗不同,饮食习惯存在差异,而导致血清微量元素锌、铁、铜、钙、镁含量的差异,这与维吾尔族子痫前期的患病率高于汉族有一定的关系。
Objective To explore the changes of serum trace elements zinc, copper, iron and manganese in Uygur preeclampsia patients and to guide the prevention and clinical treatment of preeclampsia. Methods Serum samples from 30 pregnant women with preeclampsia and 30 pregnant women from Uygur and Han nationalities with mild preeclampsia and 30 Uygur and Han Han neonates were measured with Hitachi 7600 automated biochemical analyzer and Roche automatic biochemical analyzer respectively. The levels of calcium, magnesium, zinc, iron and copper in 36 cases of Uygur and Han in severe preeclampsia and 36 cases in each of Uygur and Han nationalities of neonatal umbilical cord serum were measured and compared. Results The contents of iron, calcium and magnesium in mild Han maternal serum of preeclampsia were significantly higher than those of Uygur nationality (P <0.05), while Han people were lower in copper than Uyghur and Uygur, but the difference was not statistically significant (P> 0.05). The levels of serum calcium, magnesium and zinc in severe preeclampsia Han nationality were higher than those in Uyghur nationality (P <0.05). Han people were higher in iron content than Uyghur nationality, but lower in copper content than Uyghur nationality The difference was not statistically significant (P> 0.05). Conclusions The contents of trace elements zinc, copper, calcium and magnesium in Uygur and Han nationality patients are different and have a certain correlation with the occurrence of preeclampsia and the progression of the disease. Due to differences in living habits and beliefs and habits, differences in dietary habits may lead to differences in the contents of serum zinc, iron, copper, calcium and magnesium, which is higher than the prevalence of preeclampsia in the Uyghur Han population .