胰岛素抵抗(insulin resistance,IR)和代谢综合征(metabolic syndrome,MS)可能是慢性肾脏病(chronic kidney disease,CKD)患者的心血管危险因素。该研究检查CKD中IR和血管功能的关系,确定MS的患病率及MS和血管功能之间的相关性。方法:入选3～4期CKD患者71例,进行横断面研究评估动脉僵硬度[脉搏波传导速度(pulse wave velocity,PWV)和血管内皮功能障碍(endothelial dysfunction,ED)],采用稳态模型评估的IR指数(homeostasis Insulin resistance (IR) and metabolic syndrome (MS) may be cardiovascular risk factors in patients with chronic kidney disease (CKD). The study examined the relationship between IR and vascular function in CKD to determine the prevalence of MS and the association between MS and vascular function. Methods: Seventy-one patients with stage CKD were enrolled in this study. A cross-sectional study was performed to assess arterial stiffness (PWV) and endothelial dysfunction (ED) The IR index (homeostasis