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本文对流行性出血热各期病人56人分血清进行了免疫学检测。结果证明免疫功能有较明显改变。淋巴细胞PHA转化试验、E花环形成率均低于正常人;发热期、少尿期IgM上升,IgG偏低,至多尿期IgM随IgG开始上升而逐渐下降,与正常人相比差异显著;血清中C_3含量发热期降低,少尿期下降最显著,至多尿期始随IgM下降,IgG升高而逐渐恢复正常水平。从而提示流热的免疫学反应特点符合病毒初次感染反应规律,并且免疫复合物在发病机理上起重要作用。
In this paper, 56 patients at different stages of epidemic hemorrhagic fever were immunologically detected. The results show that there is a more significant change in immune function. Lymphocytes PHA transformation test, E rosette formation rate were lower than normal; fever, oliguria IgM increased, IgG is low, to polyuria IgM began to rise and gradually decreased, compared with normal people significant difference; serum C_3 content in the fever period decreased, the most significant oliguria decreased to polyuria began with IgM decreased, elevated IgG and gradually returned to normal levels. It is suggested that the immunological reaction characteristics of flow and heat are in accordance with the law of primary infection and the immune complex plays an important role in the pathogenesis.