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目的总结经鼻-蝶入路垂体瘤并发症的防治体会,提高疗效和患者术后生活质量。方法 2006年至2010年共收治垂体瘤患者58例,经鼻-蝶窦入路行肿瘤切除,回顾性分析手术并发症的发生情况。结果肿瘤全切49例,大部分切除9例;术后并发症:尿崩症及水电解质紊乱6例,垂体功能低下2例,复发1例,脑脊液鼻漏合并颅内感染1例。结论充分术前准备、掌握局部解剖结构、熟练的手术操作及术后护理质量是提高垂体瘤手术治疗疗效的关键。
Objective To summarize the experience of prevention and treatment of complications of pituitary tumor by nasal-butterflies approach and to improve the curative effect and quality of life of postoperative patients. Methods From 2006 to 2010, 58 patients with pituitary adenoma were treated by tumor resection via naso-sphenoid sinus and the complications of surgery were analyzed retrospectively. Results The tumors were resected in 49 cases, most of them were resected in 9 cases. Postoperative complications included 6 cases of diabetes insipidus and water electrolyte disturbance, 2 cases of pituitary dysfunction, 1 case of recurrent disease, 1 case of cerebrospinal fluid rhinorrhea and intracranial infection. Conclusion The full preoperative preparation, mastery of local anatomy, skilled operation and postoperative quality of care is the key to improve the efficacy of surgical treatment of pituitary tumors.