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目前大量资料证实免疫机制为肾小球肾炎的重要发病机理。关于血清IgE测定在各类肾小球肾炎的系统研究罕有报道,本文旨在评定血清IgE测定在各类肾小球肾炎的数值及其临床意义。选择119例由肾活检证实的原发性肾小球肾炎,平均年龄34.5±10.2岁,男女之比为86:33。病理诊断:微小病变型(MCD)22例,lgM肾病(IgMN)13例,局灶肾小球硬化(FGS)33例,膜性肾小球肾炎(MGN)22例,IgA肾病(IgAN)24例,膜增殖性肾小球肾炎(MPGN)5例,并选择33名年龄、性别与研究组相匹配的无过敏史的正常健康人作为对照组。血清IgE测定采用放射免疫吸附法。
At present, a large number of data confirm that the immune mechanism is an important pathogenesis of glomerulonephritis. Serum IgE assays are rarely reported in various systemic studies of glomerulonephritis, and this article aims to assess the value of serum IgE in various types of glomerulonephritis and its clinical significance. 119 cases of primary glomerulonephritis confirmed by renal biopsy were selected. The average age was 34.5 ± 10.2 years and the ratio of male to female was 86:33. Pathological diagnosis: 22 cases of minimal change type (MCD), 13 cases of lgM nephropathy (IgMN), 33 cases of focal glomerulosclerosis (FGS), 22 cases of membranous glomerulonephritis (MGN) Cases of membranoproliferative glomerulonephritis (MPGN) in 5 cases, and select 33 age and gender matched the study group of normal healthy without allergy as a control group. Serum IgE assay using radioimmunoassay.