论文部分内容阅读
目的:探讨抗癌药局部导入并放射治疗浅表肿瘤的临床效果。方法:对伴两个浅表病灶的肿瘤患者12例,采用自身对照的方法分为两组,较大病灶给予局部导入抗癌药合并放疗(导放组),另一病灶给予单纯放疗(单放组),两组病灶均给予常规放疗(每周5次,每次2Gy),靶区剂量(D_T)60Gy/6W.30次。结果:导放组 CR 率为83%,单放组为33%,两组差异有显著性。导放组皮肤反应明显重于单放组(P<0.01),但未影响治疗,也未增加患者的全身反应。结论:抗癌药导入并放射疗法是一种治疗浅表肿瘤的有效方法之一。
OBJECTIVE: To investigate the clinical effects of local introduction of anti-cancer drugs and radiation therapy for superficial tumors. Methods: Twelve patients with tumors with two superficial lesions were divided into two groups by self-control method. Large lesions were given local introduction of anticancer drugs combined with radiotherapy (guided release group), and another lesion was given by single radiotherapy (single Placement group), both groups of lesions were given conventional radiotherapy (five times a week, each time 2Gy), target dose (D_T) 60Gy/6W.30 times. RESULTS: The CR rate was 83% in the guide group and 33% in the radiotherapy group. There was a significant difference between the two groups. The cutaneous response in the lead group was significantly heavier than that in the single release group (P<0.01), but it did not affect the treatment and did not increase the patient’s systemic response. Conclusion: The introduction of anticancer drugs and radiation therapy is an effective method for the treatment of superficial tumors.