论文部分内容阅读
适合于头颈癌诊断的可靠循环瘤标尚未获得。本文报告了应用循环鳞状细胞癌抗原评价头颈鳞癌患者预后的效果。作者采取了89名头预鳞癌患者治愈前、后间期的血样。应用放射免疫法测定鳞癌抗原水平。经测定,89名患者中,于治疗前有39名(44％)呈现鳞癌抗原高血清水平(>2.0mg/ml)。其中治疗后复发者的血清鳞癌抗原水平与临床过程之间有显著的相关关系。16名确定有复发癌或癌残存的患者中,15名(93.5％)显示了高鳞癌抗原水平。而21名已确定为治愈性癌的患者中,仅10名
Correct circulating tumor markers suitable for the diagnosis of head and neck cancer have not yet been obtained. This article reports the use of circulating SCC antigens to assess the prognosis of patients with head and neck squamous cell carcinoma. The authors took 89 patients with pre-squamous cell carcinoma cured before and after the period of blood samples. Application of radioimmunoassay in the determination of squamous cell carcinoma antigen level. Of the 89 patients tested, 39 (44%) showed high serum levels of SCC (> 2.0 mg / ml) before treatment. There was a significant correlation between the levels of serum squamous cell carcinoma antigen and the clinical course of relapse after treatment. Of the 16 patients identified with recurrent or residual cancer, 15 (93.5%) showed high SCC antigen levels. Of the 21 patients who were identified as curative cancers, only 10 were