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以对乙酰氨基苯酚为原料合成了15个二氢苯并吡喃酮衍生物,血管扩张试验结果表明,6个化合物对低钾(20 mmol/L KCI)刺激引起的大鼠胸主动脉条收缩有较好的抑制作用。
15 dihydrobenzopyranone derivatives were synthesized from acetaminophen. The results of vasodilatation test showed that the six compounds inhibited the contraction of thoracic aorta in rats induced by low potassium (20 mmol / L KCI) Have a better inhibitory effect.