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血管紧张素原基因(AGT)M235T位点多态性与原发性高血压和妊娠高血压相关。单体型的产生可帮助决定等位基因T是否可单独做为原发性高血压发生的易感基因或只是不明原因分子变异的一个标记。我们在AGT基因位点,已鉴定了10个二等位基因的多态性,并且对一些...
The angiotensinogen gene (AGT) M235T polymorphism is associated with essential hypertension and gestational hypertension. Haplotypes can help determine whether allele T can be used alone as a predisposition to essential hypertension or as a marker for molecular changes of unknown origin. At the AGT locus, we have identified 10 polymorphisms in the two alleles and for some ...