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目的了解洛阳地区初筛Rh D阴性无偿献血人群Rh血型抗原的分布情况。方法利用广谱抗球蛋白微柱凝胶卡和Rh血型分型卡对2013年1月-2014年12月本站859份初筛阴性的献血者标本进行鉴定和分型。结果859份Ig M抗-D阴性标本中检出弱D型45份(占5.24%),Rh D阴性814份(占94.76%);Rh D阴性表现型分布以dccee(59.95%)和d Ccee(27.89%)居多,c和e抗原频率较高,分别为97.54%和99.63%;Rh弱D型献血者表型cc Ee占比例最高为60%。结论对本地区初筛Rh D阴性献血人群的Rh血型抗原分布有了具体的了解,可对本地区Rh血型系统的稀有血型队伍建设提供及时有效的参考依据。
Objective To understand the distribution of Rh blood group antigens in Rh D negative blood donors in Luoyang area. Methods A total of 859 primary negative blood donors from January 2013 to December 2014 were identified and screened by using broad-spectrum anti-globin microcolumn gel cards and Rh blood typing cards. Results 459 (5.24%) of weak D type and 814 (94.76%) of Rh D negative were detected in 859 IgM anti-D negative samples. The distribution of Rh D negative phenotype was determined by the method of dccee (59.95%) and dCcee (27.89%), c and e antigens were 97.54% and 99.63% respectively, and Rh eotype D donors had the highest proportion of 60%. Conclusion The distribution of Rh blood group antigens in Rh D negative blood donors with initial screening in this area has a specific understanding, which can provide a timely and effective reference for the construction of rare blood group in Rh blood system in this region.