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目的探讨绝经前后女性泌乳素腺瘤的不同临床特征及诊治方法。方法回顾性总结1996年1月~2004年12月诊治的26例女性患者,将其分为绝经前和绝经后两组,进行对照分析。结果绝经前组女性泌乳素腺瘤病人临床表现主要为因泌乳素增高导致月经紊乱、闭经、溢乳,病程长,易误诊,而绝经后组临床表现主要为视力下降,双颞侧偏盲。结论女性泌乳素腺瘤在绝经前和绝经后临床表现具有不同的特征,溴隐亭治疗适合于要求生育而又不愿意手术的年轻女性和妊娠期泌乳素微腺瘤妇女,经蝶入路为首选的手术方法。
Objective To investigate the different clinical features and diagnosis and treatment of prolactinomas in women before and after menopause. Methods A retrospective review of 26 female patients diagnosed and treated from January 1996 to December 2004 was divided into premenopausal group and postmenopausal group for comparative analysis. Results The clinical manifestations of prolactinoma in premenopausal women were mainly menstrual disorders, amenorrhea and galactorrhea due to the increase of prolactin. The clinical manifestations of menopausal women were mainly visual decline and bilateral temporal hemianopsia. Conclusions The clinical manifestations of prolactinomas in women before and after menopause have different characteristics. Bromocriptine is suitable for young women who require fertility and are not willing to operate and women with prolactinoma microadenoma during pregnancy. The transsphenoidal approach The preferred method of surgery.