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目的调查近3年来北京地区反流性食管炎患者幽门螺杆菌(Hp)感染率,分析目前反流性食管炎与Hp感染的相关性。方法选择反流性食管炎患者119例和正常对照组121例,以快速尿素酶试验及13C-尿素呼气试验检测Hp感染。结果反流性食管炎患者Hp感染率(26.89%),显著低于对照组(42.15%),P<0.05。结论Hp可能在反流性食管炎的发病中起到保护作用。
Objective To investigate the prevalence of Helicobacter pylori (Hp) in patients with reflux esophagitis in Beijing during the past 3 years and to analyze the correlation between current reflux esophagitis and Hp infection. Methods 119 cases of reflux esophagitis patients and 121 cases of normal control group, rapid urease test and 13C-urea breath test to detect Hp infection. Results The prevalence of Hp infection in reflux esophagitis patients (26.89%) was significantly lower than that in controls (42.15%) (P <0.05). Conclusion Hp may play a protective role in the pathogenesis of reflux esophagitis.