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过氧化物酶体增殖物激活受体γ(PPARγ)属配体激活的Ⅱ型核受体转录因子超家族成员,包括肾脏在内的多种组织表达PPARγ,噻唑烷二酮类(TZDs)是其人工合成配体,研究证实其具有多方面肾脏保护作用。本文就TZDs在进展期糖尿病肾病、慢性非糖尿病性肾病、透析、肾脏移植和慢性肾功能
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated type II nuclear receptor transcription factor superfamily member that contains PPARγ in a variety of tissues, including the kidneys, and thiazolidinediones (TZDs) are Its synthetic ligand, studies have shown that it has a variety of kidney protection. In this paper, TZDs in advanced diabetic nephropathy, chronic non-diabetic nephropathy, dialysis, kidney transplantation and chronic renal function