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目的:观察自然分娩过程应用益母草颗粒联合缩宫素对子宫收缩和产后出血的影响。方法:将自然分娩产妇104例随机分为2组各52例,对照组给予缩宫素预防产后出血,胎儿娩出后立即给予臀部肌肉注射缩宫素;治疗组在对照组的基础上加用益母草颗粒治疗;观察并记录8、16、24、48 h内宫底高度变化及2、24 h阴道出血量,评价2组子宫收缩情况及产后止血情况。结果:治疗组子宫复旧有效率为92.31%,对照组为75.00%,2组比较,差异有统计学意义(P<0.05)。治疗24、48 h后,治疗组患者子宫宫底均较对照组同期降低,差异有统计学意义(P<0.01)。治疗组产后2、24 h出血量均较对照组低,差异有统计学意义(P<0.01)。结论:在常规缩宫素治疗基础上,益母草颗粒可明显加快宫底下降,促进子宫收缩,减少产后出血量,其临床疗效高于单纯缩宫素治疗。
Objective: To observe the effects of motherwort granules combined with oxytocin on uterine contractions and postpartum hemorrhage during spontaneous labor. Methods: 104 cases of spontaneous delivery of women were randomly divided into two groups of 52 cases, the control group was given oxytocin to prevent postpartum hemorrhage, immediately after delivery of the fetus intramuscular injection of oxytocin; the treatment group in the control group based on the use of Motherwort The changes of intrauterine heights and intravaginal bleeding at 2, 24 h were observed and recorded at 8, 16, 24 and 48 hours. The contractions of uterus and postpartum hemostasis were evaluated. Results: The cure rate of uterine involution was 92.31% in the treatment group and 75.00% in the control group. There was significant difference between the two groups (P <0.05). After treatment for 24 and 48 h, the uterine fundus in treatment group was lower than that in control group at the same period (P <0.01). The bleeding volume of the treatment group at 2, 24 h postpartum was lower than that of the control group, the difference was statistically significant (P <0.01). Conclusion: Based on the conventional oxytocin treatment, Motherwort particles can significantly reduce the uterus, promote uterine contraction and reduce the amount of postpartum hemorrhage, and its clinical efficacy is higher than that of simple oxytocin treatment.