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目的 探讨病毒性肝炎患者的血清丙氨酸氨基转移酶 (ALT)和门冬氨酸氨基转移酶 (AST)、白蛋白 (A)和球蛋白 (G)的比值与病变程度的关系。方法 检测 42 4例肝炎患者ALT、AST、A、G及计算ALT/AST、A/G比值。结果 随着肝实质损害的加重 ,ALT/AST及A/G比值逐渐缩小 ,表现为ALT/AST与A/G呈同步变化 ,各型肝炎相应的ALT/AST及A/G比值差异有显著性 (P <0 0 1或P <0 0 5 )。结论 ALT/AST与A/G比值对判断病毒性肝炎的病情预后有一定的帮助 ,该方法简单易行
Objective To investigate the relationship between the serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), albumin (A) and globulin (G) in patients with viral hepatitis and the severity of the disease. Methods The ALT, AST, A, G of 42 4 hepatitis patients and ALT / AST, A / G ratio were calculated. Results With the aggravation of liver parenchyma, the ratio of ALT / AST and A / G gradually decreased. The ALT / AST showed a synchronous change with A / G, and the ALT / AST and A / G ratio of each type of hepatitis were significantly different (P <0 0 1 or P <0 0 5). Conclusions ALT / AST and A / G ratio may be helpful in judging the prognosis of viral hepatitis. The method is simple and easy to operate