论文部分内容阅读
用透射电镜对10例3～9个月胎龄的人胚胎肝脏红系造血进行了观察。发现胚胎期肝脏红系造血主要发生在肝实质组织内;3～6个月胎龄的胚胎肝脏中红系造血活跃,9个月胎龄者红系造血仍存在,但造血细胞呈局灶性分布,胚胎肝脏产生的幼红细胞在亚显微水平与正常人骨髓产生的幼红细胞无明显差异;胚胎肝细胞有适应红细胞系造血的亚显微结构,提示在胚胎一定时期内肝实质组织是有利红系细胞分化发育的微环境;胚胎期肝窦内皮细胞的不连续性和出现幼红细胞,提示造血过程中不能像骨髓那样有效地控制血细胞的释放。
Transmission electron microscopy of 10 cases of 3-9 months gestational age human erythrocyte hematopoietic were observed. Found that the embryonic liver hematopoietic hematopoietic tissue occurs mainly in the liver parenchyma tissue; 3 to 6-month gestational age embryo liver erythroid hematopoietic active 9-month-old erythroblastic hematopoiesis still exist, but the hematopoietic cells were focal Distribution, embryonic liver produced erythroblasts in the submicroscopic level of normal human bone marrow erythroblasts produced no significant difference; embryonic liver cells to adapt to erythrocyte hematopoietic submicroscopic structure, suggesting that during a certain period of embryonic liver parenchyma is beneficial Erythroid differentiation and development of microenvironment; embryonic sinusoidal endothelial cell discontinuity and the emergence of erythroid cells, suggesting that the process of hematopoietic can not be as effective as bone marrow control of blood cell release.