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目的 观察生脉注射液对家兔心肌缺血再灌注损伤的保护作用。方法 1 8只兔随机分为非缺血对照组 (A组 ) ,缺血再灌注常规治疗组 (B组 )及缺血再灌注生脉注射液治疗组 (C组 )。结果 与B组比较 ,C组心肌组织MDA含量、CPK活性及血浆ET水平明显下降 (P <0 .0 1 ) ,心肌组织T -SOD活性及血清NO水平显著增高 (P <0 .0 1 )。结论 生脉注射液可明显减轻家兔心肌缺血再灌注损伤
Objective To observe the protective effect of Shengmai injection on myocardial ischemia-reperfusion injury in rabbits. Methods Eighteen rabbits were randomly divided into non-ischemia control group (group A), ischemia reperfusion group (group B) and ischemia-reperfusion injection group (group C). Results Compared with group B, myocardial tissue MDA content, CPK activity and plasma ET levels in group C were significantly decreased (P < 0.01), T-SOD activity in myocardial tissue and serum NO levels were significantly higher (P <0. 01). . Conclusion Shengmai Injection can significantly reduce myocardial ischemia and reperfusion injury in rabbits