观察１５９例健康体检人员血清甲状腺激素水平，甲状腺有关自身抗体及血脂、载脂蛋白浓度与年龄的关系。结果发现随年龄增加，血清胆固醇（ＴＣ）、甘油三脂（ＴＧ）、载脂蛋白Ｂ（ａｐｏＢ）及促甲状腺激素（ＴＳＨ）、抗甲状腺球蛋白抗体（ＴＧＡ）呈增加趋势，其中ＴＣ、ＴＧ及ＴＳＨ与年龄成显著正相关。而血清游离三碘甲腺原氨酸（ＦＴ３）、游离甲状腺素（ＦＴ４）及高密度脂蛋白（ＨＤＬ－Ｃ）、载脂蛋白Ａｌ（ａｐｏＡｌ）则呈下降超势，且ＦＴ３、ＦＴ４与年龄呈显著负相关。提示甲状腺激素可影响血清脂蛋白代射，血脂随年龄而增高可能与老年后甲状腺机能逐渐降低有关 Serum thyroid hormone levels, thyroid-related autoantibodies and serum lipids, apolipoprotein concentrations in 159 healthy subjects were examined for their association with age. The results showed that the serum cholesterol (TC), triglyceride (TG), apolipoprotein B (apoB), thyrotropin (TSH) and anti-thyroglobulin antibody (TGA) There was a significant positive correlation between TSH and age. FT3, FT4, HDL-C, and apoAl in serum decreased, while FT3, FT4 and age Significantly negative correlation. Hint thyroid hormone can affect serum lipoprotein injection, blood lipids increased with age may be related to the gradual reduction of thyroid function after the elderly