目的:探讨基于“少阳为枢”理论运用小柴胡汤加减治疗咳嗽变异性哮喘(CAV)的疗效。方法:选择2018年5月至2019年5月淮南市中医院就诊的CAV患者23例，均经支气管扩张试验确诊为CAV。患者首诊予小柴胡汤加减，7剂，水煎服，每天1剂。复诊时根据病情变化加减药方。观察疗效、不良反应，并随访半年观察复发情况。结果:23例患者显效11例，有效9例，无效3例，总有效率为87.0%(20/23)。疗程：显效11例中有4例疗程为3周，5例为4周，2例为5周；有效9例疗程为5周。无效3例治疗6周后建议改用其他治疗。22例患者未见明显不良反应，有1例患者轻微恶心，后自行缓解。23例患者随访半年，复发3例，复发率为13.0%(3/23)。结论:基于“少阳为枢”理论运用小柴胡汤加减治疗CAV，临床总有效率高，复发率低，无明显不良反应。“,”Objective:To explore the therapeutic effect of Xiaochaihu decoction addition and subtraction on cough variant asthma(CAV) based on the theory of “ Shaoyang as the pivot” .Methods:From May 2018 to May 2019, 23 patients with CAV were selected in the Traditional Chinese Medicine Hospital of Huainan, all of whom were diagnosed as CAV by bronchodilation test.The patients were first treated with Xiaochaihu decoction addition and subtraction, 7 doses, decocting in water, oral, 1 dose per day.Add and subtract the prescriptions according to the changes of the condition.The curative effect and adverse reactions were observed, and the recurrence was observed for half a year.Results:Of 23 patients, 11 cases were obviously effective, 9 cases were effective and 3 cases were ineffective, the total effective rate was 87.0%(20/23). Course of treatment: of the 11 cases with obvious effect, 4 cases were treated for 3 weeks, 5 cases for 4 weeks, 2 cases for 5 weeks, and 9 cases with effective effect were treated for 5 weeks.It was suggested to use other treatment for 3 cases with ineffective effect after 6 weeks of treatment.No obvious adverse reactions were found in 22 patients, one patient had slight nausea, which was relieved by himself.All 23 cases were followed up for half a year, 3 cases recurred, the recurrence rate was 13.0%(3/23).Conclusion:Based on the theory of “ Shaoyang as the pivot” , the treatment of CAV with Xiaochaihu decoction addition and subtraction has high clinical effective rate, low recurrence rate and no obvious adverse reactions.