近年来研究发现,胃转流术后由于食物流向改变,肠道激素的释放明显发生了变化。肠道激素分泌的改变不仅通过肠-胰岛轴调节胰岛内分泌功能,还促进胰岛增殖和改善胰岛素抵抗,并最终影响糖代谢。胰高血糖素样多肽1、葡萄糖依赖性促胰岛素释放肽、Ghrelin、多肽YY、瘦素、脂联素、胰岛素样生长因子1等激素和细胞因子参与胃转流术后血糖调节,是目前研究的热点,现就其机制进行探讨。 In recent years, the study found that gastric bypass due to changes in food flow, intestinal hormone release significantly changed. Changes in gut hormone secretion not only regulate pancreatic endocrine function via the gut-islet axis, but also promote pancreatic islet proliferation and insulin resistance and ultimately affect glucose metabolism. Glucagon-like peptide 1, glucose-dependent insulinotropic peptide, Ghrelin, polypeptide YY, leptin, adiponectin, insulin-like growth factor 1 and other hormones and cytokines involved in the regulation of blood glucose after gastric bypass is the current study The hot spots, is to explore its mechanism.