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目的了解本地区乳腺癌的临床病理特点。方法回顾性分析148例乳腺癌的临床及病理特点,对c-erbB-2的表达与ER、PR及临床病理因素的相关性进行分析。结果 148例中女性占99.3%(147例),发病平均年龄49.2岁,41~50岁组占42.6%,51~60岁组占29.7%,多以乳腺肿块为首发症状,肿瘤直径平均3.2cm。浸润性导管癌占89.9%,淋巴结转移率52.7%。ER阳性率67.6%,PR阳性率60.8%,c-cerbB-2阳性率52.7%,c-erbB-2表达与ER、PR表达及肿瘤大小有相关性。结论本地区乳腺癌好发于41~60岁的妇女,有年轻化趋式,确诊时多数有淋巴结转移。需加强乳腺癌普查工作,早期发现,早期治疗。
Objective To understand the clinicopathological features of breast cancer in this area. Methods A retrospective analysis of 148 cases of breast cancer clinical and pathological features of c-erbB-2 expression and ER, PR and clinical pathological factors were analyzed. Results Of the 148 cases, 99.3% (147 cases) were female, the mean age of onset was 49.2 years old, 42.6% in 41-50 years old group and 29.7% in 51-60 years old group. Most of them were breast lumps with the average diameter of 3.2cm . Invasive ductal carcinoma accounted for 89.9%, lymph node metastasis rate of 52.7%. ER positive rate of 67.6%, PR positive rate of 60.8%, c-cerbB-2 positive rate of 52.7%, c-erbB-2 expression ER, PR expression and tumor size. Conclusion Breast cancer in the region occurs in women aged 41 to 60 years old, there is a trend of younger age, the majority of confirmed lymph node metastasis. Need to strengthen the census of breast cancer, early detection, early treatment.