绿脓杆菌(MSHA)菌苗是一种具有广谱抗感染效果的免疫调节剂。我们观察了20例白血病患者多次疫苗主动免疫的免疫应答反应,14例病人血中广谱抗体效价升高,临床上有很好的治疗反应,6例抗体效价无变化,而临床症状加重,最后均死于败血症。上述结果提示白血病病人对疫苗的免疫应答反应,在白血病缓解中起着重要作用,对临床早期准确判断白血病患者的预后很有意义。 Pseudomonas aeruginosa (MSHA) vaccine is an immunomodulatory agent with a broad spectrum of anti-infective effects. We observed 20 patients with leukemia vaccine active immunization of multiple immune response, 14 patients with elevated serum titers of anti-HBeAg antibodies, clinically good response to treatment, antibody titer did not change in 6 cases, and clinical symptoms Aggravated, and finally died of sepsis. These results suggest that the immune response to leukemia patients response to the vaccine plays an important role in alleviating leukemia, and it is of great significance to accurately predict the prognosis of patients with leukemia in early clinical stage.