众所周知,用粗提的抗原诱发免疫应答时,抗原竞争是一种普遍的现象.所谓抗原竞争是指一种抗原或抗原决定簇的免疫应答受到另一种抗原或抗原决定簇的抑制.作者认为,这种非特异性免疫抑制作用可以部分地通过被动免疫来消除,即在注射混合抗原前,先给予抗优势抗原的抗体.通过被动输入的抗体封闭优势抗原或抗原决定簇,消除其抗原竞争作用,从而使原先受到抑制的免疫原性微弱或无免疫原性的分子能诱导出抗 It is well known that antigen competition is a common phenomenon when crude antigen is used to induce immune response.The so-called antigen competition means that the immune response of one antigen or antigenic determinant is inhibited by another antigen or antigenic determinant , This nonspecific immunosuppressive effect can be partially eliminated by passive immunization, ie, prior to the injection of the mixed antigen, the anti-idiotypic antibody is administered first, and the passive antigen or antigenic determinant is blocked by the passive antibody, eliminating its antigenic competition , So that the previously suppressed immunogenicity of weak or non-immunogenic molecules can induce resistance