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目的了解宜昌市夷陵区TORCH[弓形虫(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV)]感染状况。方法采用免疫化学发光法,检测2015年7月-2016年6月2 211例孕早期妇女血清中TORCH-IgM抗体。结果在孕早期妇女血清TORCH-Ig M抗体筛查中,总阳性率为5.65%,其中以HSV-IgM阳性率最高(2.49%),其他组分IgM阳性率分别为CMV 1.45%、RV 1.04%和TOX 0.68%,差异有统计学意义(χ~2=29.107,P<0.001);TORCH感染率在春季最高(9.92%)(χ~2=41.341,P<0.001);春季升高的TORCH感染率伴随PM2.5季均浓度超标;城镇的孕早期妇女TORCH-Ig M抗体阳性率(7.73%)高于农村(4.50%)(χ~2=9.929,P=0.002)。结论宜昌市夷陵区孕早期妇女TORCH感染率较高,在春季尤其伴空气污染时;孕妇应尽量少到公共场所或户外活动,以降低孕妇TORCH感染风险。
Objective To investigate the infection status of TORCH TOX, RV, CMV and HSV in Yiling District, Yichang City. Methods Immunochemical chemiluminescence was used to detect TORCH-IgM antibodies in 21 211 pregnant women in the first trimester from July 2015 to June 2016. Results The positive rate of HSV-IgM was 2.49% in the screening of serum TORCH-Ig M antibody in pregnant women in the first trimester, and the positive rate of other components was 1.45% and 1.04% respectively, And TOX 0.68%, the difference was statistically significant (χ ~ 2 = 29.107, P <0.001). The highest infection rate of TORCH in spring was 9.92% (χ ~ 2 = 41.341, P <0.001) The positive rate of TORCH-Ig M antibody in early pregnant women in urban areas was higher than that in rural areas (4.50%) (χ ~ 2 = 9.929, P = 0.002). Conclusion The prevalence of TORCH infection in pregnant women in Yiling District of Yichang City is high in the spring, especially when air pollution occurs. Pregnant women should minimize the risk of TORCH infection in public places or outdoor activities.