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目的:观察恰玛古膏对中晚期大肠癌化疗后免疫指标、WBC计数及KPS评分的影响。方法:将48例中晚期大肠癌患者随机分为治疗组和观察组各24例,观察组采用联合化疗1个周期,治疗组化疗的同时口服恰玛古膏60g,3次/d,1个化疗周期的前后分别进行白细胞计数、KPS评分、免疫指标观察,并比较其变化。结果:治疗组KPS评分、免疫指标均优于观察组,差异有统计学意义;白细胞下降率低于对照组,但无统计学意义。结论:恰玛古膏能够降低中晚期大肠癌患者化疗后白细胞计数的下降率,提高化疗患者的体能状况及机体免疫功能,达到减毒的作用。
Objective: To observe the effect of Qiamangao cream on immune index, WBC count and KPS score of patients with advanced colorectal cancer after chemotherapy. Methods: Forty-eight patients with advanced colorectal cancer were randomly divided into treatment group (24 cases) and observation group (24 cases). The observation group was treated with combination chemotherapy for one cycle. The patients in the treatment group were treated with Qiamangao cream 60g three times a day Before and after the chemotherapy cycle, white blood cell count, KPS score and immune index were observed and compared. Results: The KPS score and immune index of the treatment group were better than the observation group, the difference was statistically significant; the rate of leukopenia was lower than that of the control group, but there was no statistical significance. Conclusion: Qiamangao cream can reduce the decline rate of white blood cell count after chemotherapy in patients with advanced colorectal cancer, improve the physical condition and immune function of patients with chemotherapy, and achieve the attenuation effect.