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[Objective]To study the protective effect of Rubus delavayi Franch on acute liver injury induced in mice by tetrachloromethane (CCl4) . [Methods]The model of acute liver injury induced by CCl4 was treated with ethanol extract of Rubus delavayi Franch throughout the experiment. the activity of alanine aminotransferase ( ALT) ,aspartate aminotransferase (AST) in serum ,the content of malondialdehyde (MDA) ,and glutathione (GSH) in liver were detected. [Results]Rubus delavayi Franch significantly reduced the activity of AST,ALT and the content of MDA(P <0.05) , while significantly increased the content of GSH (P <0. 05) . [Conclusion]Rubus delavayi Franch has the protective effect on acute liver injury induced by CCl4 ,which has good dose-effect relationship,while the mechanism needs to be further studied.
[Objective] To study the protective effect of Rubus delavayi Franch on acute liver injury induced in mice by tetrachloromethane (CCl4. [Methods] The model of acute liver injury induced by CCl4 was treated with ethanol extract of Rubus delavayi Franch throughout the experiment. the activity of alanine aminotransferase (ALT), aspartate aminotransferase (AST) in serum, the content of malondialdehyde (MDA), and glutathione (GSH) in liver were detected. [Results] Rubus delavayi Franch significantly reduced the activity of AST, ALT and The content of MDA (P <0.05), while significantly increased the content of GSH (P <0.05). [Conclusion] Rubus delavayi Franch has the protective effect on acute liver injury induced by CCl4, which has good dose-effect relationship while the mechanism needs to be further studied.