[摘要] 目的 分析在肺癌免疫检查点抑制剂治疗患者中应用规范化管理配合全程管理的效果以及对依从性的影响。 方法 将2019年1—12月在我院接受免疫治疗的59例肺癌患者纳入研究，并随机设为两个组别，给予对照组（29例）常规护理管理，给予实验组（30例）规范化管理配合全程管理。观察两组患者管理后的心理状况和治疗依从性，评价患者自我管理效能和生活质量，记录不良症状发生情况。 结果 实验组管理后SAS、SDS评分均低于对照组，差异具有统计学意义（P<0.05）。实验组管理后自我管理效能评分和治疗依从性评分均高于对照组，差异有统计学意义（P<0.05）。在生活质量各项评分中，实验组均低于对照组，差异有统计学意义（P<0.05）。对比两组患者不良反应发生率，实验组明显更低，差异有统计学意义（P<0.05）。 结论 规范化管理配合全程管理应用于肺癌免疫治疗患者中，能够有效缓解负性心理，提高自我管理能力和治疗依从性，降低不良症状发生率，改善生活质量，应用价值明显。
　　[关键词] 肺癌;免疫检查点抑制剂;规范化管理;全程管理;依从性
　　[Abstract] Objective To analyze the effect of standardized management combined with whole-course management and its impact on compliance in the treatment of patients with lung cancer immune checkpoint inhibitors. Methods Fifty-nine lung cancer patients who received immunotherapy in our hospital from January to December 2019 were included in the study， and were randomly divided into two groups. The control group（29 cases） was given routine care management and the experimental group（30 cases） was given standardized management cooperating with the whole process management. The psychological status and treatment compliance of the two groups after management was observed. The self-management efficiency and quality of life of the patients was evaluated， and the occurrence of adverse symptoms was recorded. Results The SAS and SDS scores of the experimental group were lower than those of the control group， and the difference was statistically significant（P