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目的 研究广州城乡居民骨量峰值及其特点和影响中青年妇女骨量的因素 ,为原发骨质疏松症的诊断和预防提供有用的数据。方法 随机抽取广州地区 2 0~ 4 9岁城乡正常男女性居民 4 80人 ,先行问卷调查再进行腰椎 (L2~ 4 )正位和髋部的双能X线骨密度 (BMD)的测量。结果 男性腰椎和髋部骨量峰值 (PBM)出现在 2 0~ 2 9岁 ,L2~ 4 的PBM值为 1 14 0± 0 0 12 9(g cm2 ) ,BMD随年龄增长而下降。女性腰椎和髋部PBM出现在 30~ 39岁 (髋部的Ward’s区出现在 2 0~ 2 9岁 ) ,L2~ 4 的PBM为 1 138± 0 0 99(g cm2 ) ,男女性无显著差异。髋部PBM男性高于女性差异有显著性。 4 0~ 4 9岁不论L2~ 4 和髋部BMD女性都高于男性差异有显著性。妊娠、分娩、哺乳、避孕药、输卵管结扎术对骨量影响无显著性。结论 广州地区女性的PBM近似北京及上海地区高于成都地区。 4 0~ 4 9岁女性腰椎及髋部BMD都高于男性 ,可能与广州地区女性从事较重农业劳动有关。男性则低于沈阳、北京、上海而高于成都
Objective To study the peak value of bone mass in urban and rural areas of Guangzhou and its characteristics and influencing factors of bone mass in young and middle-aged women, and to provide useful data for the diagnosis and prevention of primary osteoporosis. Methods A total of 4880 healthy male and female residents from 20 to 49 years old in urban and rural areas of Guangzhou were randomly selected. The questionnaires were used to measure the BMD of lumbar spine (L2 ~ 4) and hip. Results The bone mass peak (PBM) of lumbar spine and hip of male was between 20 and 29 years old. The PBM of L2 ~ 4 was 1 14 0 ± 0 0 12 9 (g cm2). BMD decreased with age. The PBM of the lumbar spine and hip in women ranged from 30 to 39 years old (20 to 29 years old in the Ward’s area of the hip) and 1,138 ± 0 099 (g cm2) in L2 to 4, with no significant difference between men and women . Hip PBM male than female differences were significant. 4 0 ~ 4 9 years old regardless of L2 ~ 4 and hip BMD women were higher than men, the difference was significant. Pregnancy, childbirth, breastfeeding, contraceptives, tubal ligation had no significant effect on the bone mass. Conclusion The female PBM in Guangzhou is similar to that in Beijing and Shanghai and higher than that in Chengdu. The BMD of lumbar spine and hip in 4 0 ~ 49 years old women were higher than that of males, which may be related to the fact that women in Guangzhou were engaged in heavy agricultural work. Men are lower than Shenyang, Beijing, Shanghai and Chengdu