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目的探讨胚胎发育不良性神经上皮瘤(DNT)的诊断和治疗。方法2001年11月至2005年2月共收治DNT患者18例。对临床表现、影像学检查、术前诊断、治疗及病理作回顾性分析。结果癫痫为主要临床表现;磁共振成像(MRI)为无占位效应的病变;病理上特异性胶质神经元和多发结节为其特点;外科手术治疗,癫痫控制良好。结论DNT为良性病变,需外科治疗,手术时全切除肿瘤及术中采用皮层脑电图监护可提高手术疗效。
Objective To investigate the diagnosis and treatment of embryonic dysplastic neuroepithelioma (DNT). Methods From November 2001 to February 2005, 18 patients with DNT were admitted. The clinical manifestations, imaging studies, preoperative diagnosis, treatment and pathology for retrospective analysis. Results Epilepsy was the main clinical manifestation. Magnetic resonance imaging (MRI) was a lesion with no mass-bearing effect. Pathological-specific glial neurons and multiple nodules were the characteristics of these lesions. Surgical treatment and epilepsy were well controlled. Conclusions DNT is a benign lesion and requires surgical treatment. Surgical resection of the tumor and surgical monitoring of cortical EEG can improve the curative effect.