论文部分内容阅读
目的观察血糖控制未达标2型糖尿病患者血糖波动与认知功能的关系。方法采用问卷调查的方法评定认知功能,比较不同血糖波动组间认知功能的差异,并对认知功能与问卷当日的血糖波动情况等进行相关性分析。结果 (1)日7次血糖的均数、标准差、血糖波动及总血糖在不同HbA_1c组间有统计学差异(P<0.01);(2)不同血糖波动组间认知功能有统计学差异(P<0.05),但性别、年龄、受教育年限等方面却无统计学差异(P>0.05);(3)认知功能与检查当日7次血糖的平均值、最高血糖水平、最低血糖水平、血糖波动幅度及总血糖水平等均呈负相关。结论血糖控制未达标2型糖尿病患者认知功能与血糖波动密切相关。减少血糖波动对认知功能的保护有着重要的意义。
Objective To observe the relationship between blood glucose fluctuation and cognitive function in patients with type 2 diabetes mellitus under blood glucose control. Methods The questionnaire was used to evaluate the cognitive function, and the differences of cognitive function between different blood glucose fluctuation groups were compared. The correlation between the cognitive function and the blood sugar fluctuation on the questionnaire was analyzed. Results (1) The average number of blood glucose, standard deviation, blood glucose fluctuation and total blood glucose in seven HbA_1c groups were significantly different (P <0.01); (2) There were significant differences in cognitive function among different HbAlc groups (P <0.05), but there were no significant differences in gender, age, education years and so on (P> 0.05); (3) The average of 7 times of blood glucose, the highest blood glucose level and the lowest blood glucose level , Blood glucose fluctuations and total blood glucose levels were negatively correlated. Conclusion There is a close relationship between cognitive function and blood glucose fluctuation in patients with type 2 diabetes who do not achieve glycemic control. Reducing blood glucose fluctuations on the protection of cognitive function is of great significance.