作者晚近观察了10例终末期肾衰、接受血液透析(血透)患者应用大剂量速尿的效应。10例患者尚有残余肾功能(平均2.6±2.1毫升/分),给予速尿1.0克口服,每日2次,连用7天。与不用药期对照结果表明,所有患者的尿量增加,平均为109％(P<0.005);尿钠、氯和钾排泄亦增加,分别平均为210％,366％和65％(P<0.005);尿素排泄轻度增加,平均为29％(P<0.01),尿蛋白排泄无显著 The authors recently observed 10 cases of end-stage renal failure, hemodialysis (hemodialysis) patients with high-dose furosemide effect. Ten patients had residual renal function (mean, 2.6 ± 2.1 ml / min), given furosemide 1.0g orally twice daily for 7 days. Urinary sodium, chloride and potassium excretion also increased excreted by an average of 109% (P <0.005), with an average of 210%, 366%, and 65%, respectively ); Excretion of urea slightly increased, with an average of 29% (P <0.01), urinary protein excretion was not significant