论文部分内容阅读
粘膜接种蛋白和多肽抗原诱导的免疫应答通常较弱 ,粘膜免疫接种的成功极大程度上依赖于有效粘膜佐剂的研制。本实验研究了在非离子型嵌段共聚物 Pluronic○RF1 2 7( F1 2 7) /脱乙酰壳多糖或溶血卵磷脂 ( LPC)存在的情况下 ,粘膜接种破伤风类毒素 ( TT)所诱导的全身和粘膜免疫
Mucous inoculation protein and polypeptide antigen-induced immune response is usually weak, the success of mucosal immunization depends largely on the development of effective mucosal adjuvant. This experiment investigated the effects of mucosal inoculation of tetanus toxoid (TT) in the presence of a non-ionic block copolymer Pluronic® RF1 2 7 (F1 2 7) / chitosan or lysolecithin (LPC) Systemic and mucosal immunity