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目的调查卵巢癌患者住院化疗期间的抑郁和社会支持情况,了解卵巢癌患者抑郁的主要相关影响因素,为采取有针对性的预防措施提供科学依据。方法采用整群抽样的方法抽取了110名于2008年11月-2009年2月在湖南省肿瘤医院、中南大学湘雅二医院、湘雅医院住院化学治疗的卵巢癌患者。使用自制的调查表收集患者的一般资料,自评抑郁量表(Self-Rating Depression Scale,SDS)测量患者的抑郁情况及社会支持评定量表(Social Support Scale,SSS)测量患者的社会支持情况。采用卡方检验、秩和检验、Pearson分析巢癌患者抑郁的影响因素,Logistic多因素回归分析方法分析患者抑郁的相关影响因素。结果110例住院的卵巢癌患者的抑郁发生率为71.82%,其中轻度抑郁占38.18%,中度抑郁占25.44%,重度抑郁占8.20%。不同的年龄(P=0.00)、不同的文化程度(P=0.00)、不同的年人均收入(P=0.00)、不同的化疗次数(P=0.035)、不同的医疗费用支付方式(P=0.027)等抑郁的差异有统计学意义,居住地(P=0.021)、职业(P=0.072)等的差异无统计学意义。主观支持(P<0.01)和支持利用度(P<0.01)与抑郁呈负相关,差异有统计学意义。Logistic回归分析结果显示,支持利用度和主观支持是抑郁的保护因素,化疗次数是可能的危险因素。结论医务人员应注重住院的卵巢癌患者的主观感受到的支持,提高社会支持的利用度,降低化疗的副作用,从而降低患者的抑郁水平,增进其心理健康。
Objective To investigate the prevalence of depression and social support in patients with ovarian cancer during hospitalization and to understand the main related factors of depression in patients with ovarian cancer and to provide scientific basis for taking targeted preventive measures. Methods A total of 110 patients with ovarian cancer who underwent chemotherapy in Hunan Cancer Hospital, Xiangya Second Hospital of Central South University and Xiangya Hospital from November 2008 to February 2009 were enrolled in this study. Self-rated Depression Scale (SDS) was used to measure the patient’s depression and the social support scale (SSS) to measure the social support of the patients. Using chi-square test, rank sum test, Pearson analysis of factors affecting depression in patients with nest cancer, Logistic regression analysis of factors associated with depression. Results The incidence of depression in 110 hospitalized patients with ovarian cancer was 71.82%, with mild depression accounting for 38.18%, moderate depression accounting for 25.44%, and severe depression accounting for 8.20%. (P = 0.00), different per capita income (P = 0.00), different chemotherapy times (P = 0.035), different medical expenses payment methods (P = 0.027) ) And other depression were statistically significant differences in place of residence (P = 0.021), occupation (P = 0.072) and other differences were not statistically significant. Subjective support (P <0.01) and supportive utilization (P <0.01) were negatively correlated with depression, the difference was statistically significant. Logistic regression analysis showed that support utility and subjective support were the protective factors of depression, and the frequency of chemotherapy was a possible risk factor. Conclusion Medical staff should pay attention to the subjective support of hospitalized patients with ovarian cancer, improve the utilization of social support and reduce the side effects of chemotherapy, thereby reducing depression and improving their mental health.