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目的:观察甲基强的松龙联合盐酸溴己新治疗儿童毛细支气管炎的临床效果。方法:将我院收治的120例毛细支气管炎患儿随机分为2组,即观察组60例,对照组60例。入院后,2组患者均行常规治疗,观察组患儿在常规治疗的基础上行甲基强的松龙联合盐酸溴己新治疗,对照组患儿在常规治疗的基础上行单纯的甲基强的松龙治疗。分别对2组患儿的临床治疗效果进行评价,同时观察并统计2组患儿喘憋、咳嗽、发热、口唇发绀及肺部哮鸣音等临床症状及体征的消失时间。结果:观察组患儿临床治疗的总有效率为95%,对照组为83.33%,2组比较,差异具有统计学意义(P<0.05)。观察组患儿喘憋、咳嗽、发热、口唇发绀及肺部哮鸣音消失平均时间明显短于对照组,2组比较,差异具有统计学意义(P<0.05)。结论:甲基强的松龙联合盐酸溴己新治疗儿童毛细支气管炎的临床疗效明显优于单纯的甲基强的松龙治疗,值得临床推广与应用。
Objective: To observe the clinical effect of methylprednisolone combined with bromhexine hydrochloride in children with bronchiolitis. Methods: 120 cases of bronchiolitis admitted to our hospital were randomly divided into two groups, 60 cases in the observation group and 60 cases in the control group. After admission, the patients in both groups underwent routine treatment. The children in the observation group were treated with methylprednisolone and bromhexine hydrochloride on the basis of routine treatment. The children in the control group were treated with simple methylprednisolone Pineel treatment. The clinical effects of two groups of children were evaluated respectively. At the same time, the disappearance time of clinical symptoms and signs such as wheezing, cough, fever, cyanosis of the lips and lung wheezing were observed and counted. Results: The total effective rate of clinical treatment in observation group was 95% and that in control group was 83.33%. There was significant difference between two groups (P <0.05). The mean time of disappearance of asthmatic wheezing, coughing, fever, cyanosis of lips and lung wheezing in observation group was significantly shorter than that in control group. There was significant difference between the two groups (P <0.05). Conclusion: The clinical efficacy of methylprednisolone and bromhexine hydrochloride in the treatment of children with bronchiolitis is obviously superior to that of methylprednisolone alone, which deserves clinical application and promotion.