Minqin Oasis is located in the lower reaches of the Shiyanghe River Basin, northeast of the Heixi Corridor, at the middle of the Silk Road. Because of the its existence, Badain Jaran Desert and Tengger Desert cannot converge and develop in the south. It has always been an important green barrier to guarantee the eco-security of Hexi Corridor and the Silk Road for thousands of years. But in recent decades, Minqin Oasis is becoming smaller and the desert is becoming larger.Many people, especially the governmental officials in the lower reaches think that the upper and middle reaches have robbed the lower reaches of water resources, and caused insufficient water usage and the deteriorated eco-environment, in the lower reaches, However, the governmental officials in the upper and middle reaches claim that the whole river basin should take the upper and middle reaches as the key regions to develop economy. To address the above argument, we analyze the reasons why Minqin Oasis is disappearing, and find that there are two main factors. One is the quick development of population and economy in the upper and middle reaches; the other is the rapid development of population and economy in the lower reaches. The two factors both have great effect on the water utilization for eco-environment in the lower reaches. So Minqin Oasis is disappearing not only because of the upper and middle reaches but also because of the growth of population and economy itself. The lower reaches should not completely blame the upper and middle reaches. The upper and middle reaches should also pay more attention to the eco-environment in the lower reaches. The whole river basin should develop a harmonious and sustainable relationship among the upper, middle and lower reaches.