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目前肾上腺糖皮质激素(下称皮质激素)在临床应用已越来越广。而且泛用和滥用的现象颇为严重,以致皮质激素所致的药源性疾病多于其它任何一类药物,发生率高达8.3～20.2％。其中约5～10%为严重的副作用。因此,必须全面认识皮质激素的利弊,尽可能使临床应用合理。 皮质激素超生理量引起的副作用和并发症 (一)、医源性肾上腺皮质功能亢进症: 长期应用皮质激素的病人因水、盐代谢以及糖、蛋白质和脂肪代谢等紊乱,约有66～75％可出现医
At present, adrenal glucocorticoid (hereinafter referred to as corticosteroids) has become more widely used in clinical practice. And the phenomenon of pandemic and abuse is quite serious, leading to corticosteroid drug-induced diseases more than any other type of drug, the incidence as high as 8.3 to 20.2%. About 5 to 10% of them are serious side effects. Therefore, we must fully understand the pros and cons of corticosteroids, as far as possible to make the clinical application of reasonable. Side effects and complications caused by corticosteroid super-physiological (a), iatrogenic adrenal insufficiency: patients with long-term use of corticosteroids due to water, salt metabolism and sugar, protein and fat metabolism and other disorders, about 66 ~ 75 % Can appear medical