目的分析AxSYM与RP-HPLC两种方法测定卡马西平血药浓度结果相关性。方法利用AxSYM和RP-HPLC两种方法同时测定卡马西平血药浓度,以AxSYM测定值为X,RP-HPLC测定值为Y进行线性回归,评价其相关性。结果92组数据经线性回归得回归方程:Y=0.013 731+0.969 354X(n=92,r=0.992 451)。结论AxSYM测定卡马西平血药浓度结果与RP-HPLC测定结果具有较好相关性,适用于卡马西平血药浓度的常规监测。 Objective To analyze the correlation between the concentration of carbamazepine and AxSYM and RP-HPLC. Methods Both AxSYM and RP-HPLC methods were used to determine the plasma concentration of carbamazepine simultaneously. The linear regression was performed using AxSYM and X as standard, and the correlation was determined by linear regression. Results 92 sets of data were linear regression regression equation: Y = 0.013 731 + 0.969 354X (n = 92, r = 0.992 451). Conclusion AxisYM determination of carbamazepine plasma concentration results and RP-HPLC determination of the results have a good correlation, suitable for routine monitoring of plasma carbamazepine concentration.