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目的 :探讨妊娠期糖代谢异常孕妇孕期血糖控制满意后 ,新生儿早期动态血糖变化。方法 :选择 1998年4月至 1999年 11月北京大学第一医院糖代谢异常孕妇孕期血糖控制满意者所分娩的新生儿 30例 ;糖代谢正常孕妇所分娩的新生儿 6 0例 ,其中大于胎龄儿 2 6例 ,正常体重儿 (对照组 ) 34例。新生儿出生后分别于第 2、4、8、2 4小时测定微量血糖 ,并监测血色素、红细胞压积、微量胆红素及体温等。结果 :糖代谢异常孕妇血糖控制满意组新生儿出生 2、4、8、2 4h微量血糖值 [(3 .3± 0 5 ) ,(3 .4± 0 .4) ,(3 .6± 0 .5 ) ,(3 .6± 0 .6 )mmol·L-1, x±s]与对照组[(3 .2± 0 .4) ,(3.3± 0 .4) ,(3 .3± 0 .4) ,(3.4± 0 .3)mmol·L-1, x±s]相比 ,差异无显著性 (P >0 .0 5 ) ,无低血糖发生 ;且新生儿出生体重也与对照组相近。结论 :严格控制糖代谢异常孕妇孕期血糖 ,可使新生儿出生早期血糖与糖代谢正常母亲的新生儿相近 ,且降低新生儿早期低血糖的发生
Objective: To investigate the abnormal glucose metabolism in pregnant women during pregnancy glycemic control satisfaction, neonatal dynamic blood glucose changes. Methods: From April 1998 to November 1999, Peking University First Hospital, 30 cases of abnormal glucose metabolism in pregnant women pregnant women with satisfactory control of blood glucose were delivered by newborns; normal glucose metabolism in pregnant women delivered 60 newborns, of which more than fetal 26 cases of age children, normal weight children (control group) 34 cases. After birth, blood glucose, hemoglobin, hematocrit, trace bilirubin and body temperature were measured at 2,4,8,2,4 hours after birth respectively. Results: The blood glucose levels in neonates with 2,4-and 24-hour, 24-hour and 24-hour after birth were significantly lower than those in those with abnormal glucose metabolism [(3. 3 ± 0 5), (3.4 ± 0 4), (3.6 ± 0 .5), (3.6 ± 0.6) mmol·L-1, x ± s] compared with the control group [(3.2 ± 0.4), (3.3 ± 0.4), (3.3 ± (P <0.05), no hypoglycaemia, and the birth weight of newborns was also significantly higher than that of (3.4 ± 0.3) mmol·L-1, x ± s Control group similar. Conclusion: Strict control of glucose metabolism in pregnant women during pregnancy, blood sugar can make the early birth of newborn blood glucose and glucose metabolism of normal mothers similar to newborns, and reduce the incidence of neonatal hypoglycemia