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近年来,随着提取、分离和结构鉴定技术的迅速发展,中草药中许多抗真菌有效成分如萜类、皂苷、酮类、蛋白质等得到发掘。而且许多研究表明,中草药可通过破坏真菌的结构、阻断真菌结构及大分子的生物合成、干扰真菌的能量代谢,或通过调节人体免疫功能,或通过对其他抗真菌药物的增效作用来杀灭或抑制真菌;研究中草药的抑菌方法也不断走向完善化、标准化;中草药用于治疗真菌病在外用及内服等方面均有很好的临床疗效,具有广阔的应用前景。
In recent years, with the rapid development of extraction, separation, and structure identification techniques, many antifungal active ingredients such as terpenes, saponins, ketones, and proteins have been discovered in Chinese herbal medicines. And many studies have shown that Chinese herbs can kill by destroying the structure of fungi, blocking the structure of fungi and the biosynthesis of macromolecules, interfering with the energy metabolism of fungi, or by regulating the body’s immune function, or by synergies with other antifungal drugs. Elimination or inhibition of fungi; antibacterial methods of Chinese herbal medicine research continue to improve, standardization; Chinese herbal medicine for the treatment of fungal diseases in external use and oral administration have a very good clinical efficacy, has broad application prospects.